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Effectiveness of Electrolyzed Oxidized Water Irrigation in a Burn-Wound Infection ModelHajime Nakae, MD, PhD, The Journal of TRAUMA Injury, Infection, and Critical Care 2000;49:511–514. Abstract Objective: The purpose of the study was to determine whether electrolyzed oxidized water (EOW) functions as a bactericide in burn injury with Pseudomonas aeruginosa infection in a rat burn-wound model. Methods: Anesthetized Sprague-Dawley rats (n = 31) were subjected to third-degree burns to 30% of total body surface area. Two days after injury, all rats were infected with P. aeruginosa using 1 mL of a suspension containing 1 x 108 colony-forming units. Rats were assigned to one of three groups: no irrigation (group I), irrigation with physiologic saline (group II), or irrigation with EOW (group III). Blood culture, endotoxin levels, and survival rates were determined. Results: Survival rate was significantly higher in group III than in groups I or II (p < 0.0001). Serum endotoxin levels on day 3 after infection in group III were significantly lower than the levels in group I (p < 0.01) and group II (p < 0.01). There were significant differences between the three groups in the culture of P. aeruginosa (p < 0.05). Conclusion: Irrigation and disinfection with EOW may become useful in preventing burn-wound sepsis. Key Words: Electrolyzed oxidized water, Burn-wound To download the .pdf of the entire study, please click here. For More Information Charme is one of the best skin care products you will find to create a low pH on the surface of your skin. This naturally will fight off the bacteria that causes various skin affilictions. Other clinical studies and clinical trials of effective skincare products.
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